Letsou Quoted in DNA Mutation Story
, assistant professor of biological and chemical sciences, lent his expertise to an聽 article about the use of Google’s DeepMind AI tool to detect mutations in human DNA. Letsou, a computational biologist who conducts breast cancer mutation research, noted the tool’s potential to accelerate research in this area by improving experimental efficiencies.聽
鈥淭he DeepMind tool assesses how changes at each missense variant of every human protein affect protein structure, saving immense experimental effort,鈥 he said. 鈥淭he alternative to DeepMind’s variant pathogenicity tool is to generate and crystallize each variant of a protein and look for gross structural alterations. Not only is the experimental work costly and time-consuming, but there are thousands of potential variants to try for each protein.鈥
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