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Pictured: Assistant Professor Milan Toma

A recent study by  (NYITCOM) faculty and alumni provides new insight into how military blasts can injure unborn babies (fetuses) and how the amniotic fluid surrounding the fetus may provide protection. The findings, which were published in the journal , could help doctors better assess fetal injuries and inform the development of future safety devices.

Pregnancy-related trauma is one of the  of morbidity and mortality in pregnant women and their unborn babies. Recently, military conflicts in Eastern Europe and the Middle East, where there have been documented cases of airstrikes targeting maternity hospitals, have led scientists and medical professionals to consider how the forces of a military blast could impact unborn children. 

Now, researchers, led by biomedical engineer and NYITCOM Assistant Professor Milan Toma, Ph.D., have used elaborate 3-D models to simulate the impact of an explosion beneath a motor vehicle. The models accounted for real patient-specific geometries and fluid-structure interaction in spaces between the inner lining of the uterus and fetus, placenta, and umbilical cord. 

Their findings showed that amniotic fluid is crucial in protecting the fetus from trauma. While the simulated explosion subjected the outside of the uterus to multiple acceleration changes, the fetus (inside the uterus) experienced lesser acceleration changes. The models also showed that because the fetus was positioned with its head facing down and exposed to an explosion underneath the mother’s womb, the area around the skull sustained more stress.

The study was conducted in collaboration with Jonathan Arias (D.O. ’23)Ìý²¹²Ô»åÌýGregory Kurgansky (D.O. ’23), former NYITCOM students who have since completed their studies and advanced to residency programs. Other collaborators included Ong Chi Wei, Ph.D., from Singapore’s Institute of High Performance Computing, and Rosalyn Chan-Akeley, M.D., an OB-GYN affiliated with Lang Research Center at New York-Presbyterian Hospital Queens.